The Vicious ‘Sleep-Seizure’ Cycle in Epilepsy

Medscape, Dec. 15, 2015
This suggests that orexin levels in the brain contribute to sleep problems, which may make seizures worse. At the same time, more severe seizures may promote sleep problems. “It’s a vicious cycle,” said Kristine Simeone, PhD, assistant professor, Department of Pharmacology, Creighton University School of Medicine, Omaha, Nebraska.
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